Best Varicose Veins Treatment in Jaipur
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Varicose veins are enlarged veins near the skin’s surface, often found in the legs due to increased pressure from standing and walking. For Best Varicose Veins Treatment in Jaipur, Dr. Manish Rajput provides advanced, personalized care using modern techniques to help you achieve healthier, smoother legs and a better quality of life.
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This lecture was presented at the 142nd Congress of the German Society of Surgery (DCK 2025), held at the Congress Center Munich from 18 to 20 March 2025, in the session HPB International, with the original title "Personalizing surgical strategy in HPB surgery".
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Biophysics Thermodynamics 1 Chapter NotesPKLI-Institute of Nursing and Allied Health Sciences Lahore , Pakistan. Biophysics – Unit 01: Thermodynamics
This unit introduces the fundamental principles of thermodynamics and their application in biological and physiological systems. It explores how energy is exchanged and transformed in the human body, forming the basis of many critical clinical processes.
Key Concepts Covered:
System & Surroundings: Open, closed, and isolated systems relevant to physiological environments (e.g., respiratory system as an open system).
Zeroth Law: Basis for clinical thermometry and body temperature regulation.
First Law of Thermodynamics (Law of Energy Conservation): Application in calorimetry, metabolic rate calculation, and ATP energy balance.
Second Law of Thermodynamics: Directionality of biological processes, entropy, and energy efficiency in muscle contraction and enzymatic activity.
Third Law: Conceptual relevance in absolute zero and physiological limits.
Clinical Applications:
Energy transformations during cellular respiration
Thermal regulation and homeostasis in patients
Bioenergetics in critical care (e.g., post-operative energy needs, fever metabolism)
Use of thermodynamic principles in medical devices (ventilators, incubators, dialysis machines)
Spondyloepiphyseal dysplasia is a mimicker of arthritis
Spondyloepiphyseal dysplasia is a mimicker of arthritisRitasman Baisya Musculoskeletal involvement in children is often challenging, with a wide range of benign conditions, such as growing pain, to severe systemic diseases. Spondylo-epiphyseal dysplasia (SED) is an autosomal recessive disease of the skeletal system that often mimics juvenile idiopathic arthritis (JIA) with no response to anti-rheumatic therapy.
Case - A young male, 22 years of age, presented with a history of pain in his upper and lower back and multiple small and large joints since five years of age. He denied any morning stiffness or increased nocturnal pain. Previously, he was treated outside as juvenile idiopathic arthritis with methotrexate, sulfasalazine and injection Adalimumab. However, his mother denied any symptomatic improvement of his pain. On examination, his growth was stunted with significant kyphoscoliosis. (Figure 1 ) He had an antalgic gait with exaggerated lumbar lordosis. He had mild tenderness in both hips, knees and ankles with flexion contracture and bony swelling at bilateral proximal & distal interphalangeal joints (PIP and DIP), referred to as camptodactyly. (Figure 2 ) His cervical and lumbar movement was severely restricted, with bilateral hip movement restricted. Laboratory investigation showed normal ESR CRP. Rheumatoid factor was low titre positive, anti-CCP antibody and HLA-B27 by PCR were negative. His skeletal radiographic images showed platyspondyly in the thoracolumbar spine, epiphyseal widening in MCP and IP joints with ovoid carpal bones (Figure 3), platyspondyly in the thoracolumbar spine (Figure 4) , hip joint sclerosis . (Figure 5 ) His diagnosis was reconsidered as spondyloepiphyseal dysplasia (SED) . He was started with extensive physiotherapy and symptomatic pain relief treatment and noticed improvement in his pain and quality of life.
Brief discussion - SED predominantly involves articular cartilage, which results in joint stiffness and epiphyseal enlargement. Typically starting at 2-8 years of age, they manifest with pain, stiffness and swelling of extremity joints. (1) On examination, the swelling is predominantly bony without any evidence of inflammation. Over time, the large joints and the spine get involved, causing significant joint contractures, gait abnormality, kyphoscoliosis, abnormal posture and poor quality of life. There are reported cases where SED have been misdiagnosed as JIA with no response to immunomodulatory treatment. (1,2) SED's radiological features differ from JIA, with platyspondyly being an early finding in the skeletal image, epiphyseal enlargement, and lack of destructive joint erosions. Though SED is considered a rare entity, one large study by Dalal et al. (3) reported 35 cases of SED from 25 unrelated families with 11 different homozygous mutations and one instance of compound heterozygosity in the WISP3 gene. It proves that this entity is not very uncommon in India.
Luteal phase support in Assisted Reproducton.pdf
Luteal phase support in Assisted Reproducton.pdfAhmed Mowafy Luteal phase support in Assisted Reproducton.pdf
Molecular Biology & Genetics cell function and structure 1.pptx
Molecular Biology & Genetics cell function and structure 1.pptxBolan University of Medical and Health Sciences ,Quetta its all about precise intro of molecular medicine and cell . course outline reflecting genetics for nursing and DPTians,
by Dr Aliya BUMHS,QTA
CHILDBIRTH POSITION DURING LABOR AND DELIVERYpptx
CHILDBIRTH POSITION DURING LABOR AND DELIVERYpptxdaminipatel37 VARIOUS CHILDBIRTH POSITION OF LABOUR , USED NOW A DAYS IN BIRTHING CENTER
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Larsen's Human Embryology.pdfembryology for medical studentsKalluKullu embryology for medical students,E verystudentwillbeaffectedbypregnancy,eithertheirmother’s,
because what happens in the womb does not necessarily stay in
the womb, or by someone else’s. As health care professionals, you will often
encounter women of childbearing age who may be pregnant, or you may
have children of your own, or maybe it is a friend who is pregnant. In any
case, pregnancy and childbirth are relevant to all of us, and unfortunately,
these processes often culminate in negative outcomes. For example, 50% of
all embryos are spontaneously aborted. Furthermore, prematurity and birth
defects are the leading causes of infant mortality and major contributors to
disabilities. Fortunately, new strategies can improve pregnancy outcomes,
and health care professionals have a major role to play in implementing
these initiatives. However, a basic knowledge of embryology is essential to
the success of these strategies, and with this knowledge, every health care
professional can play a role in providing healthier babies.Clinical Correlates: In addition to describing normal events, each
chapter contains clinical correlates that appear in highlighted boxes. This
material is designed to demonstrate the clinical relevance of embryology
and the importance of understanding key developmental events as a first
step to improving birth outcomes and having healthier babies. Clinical
pictures and case descriptions are used to provide this information, and
this material has been increased and updated in this edition.
Genetics: Because of the increasingly important role of genetics and
molecular biology in embryology and the study of birth defects, basic
genetic and molecular principles are discussed. llqe first chapter provides
an introduction to molecular processes, defines terms commonly used
in genetics and molecular biology, and describes key pathways used
Ganglion cyst -The Silent Swell : Unveiling the Mystery of the Ganglion Cyst
Ganglion cyst -The Silent Swell : Unveiling the Mystery of the Ganglion CystArghadeep Sarkar this ppt consisting of the non cancerous , asymptomatic joint swelling -ganglion cyst.
the ppt consisting the overview of ganglion cyst.
Introduction to ergonomics Lecturs 1(a).pptx
Introduction to ergonomics Lecturs 1(a).pptxBolan University of Medical and Health Sciences ,Quetta The science of fitting jobs to people, and biomechanics, the study of human movement, are closely related and both important for workplace health and safety. Ergonomics aims to optimize the interaction between humans and their work environment to minimize stress and improve well-being. Biomechanics provides the scientific basis for understanding how human movements and forces affect the body, informing ergonomic interventions to prevent injuries and improve productivity.
Dr Aliya S.M
BUMHS,Qta
Medical Negligence and Medical Ethics.pptx
Medical Negligence and Medical Ethics.pptxDr Kadiyali. M. Srivatsa Negligence & Medical Ethics – The Unspoken Pandemic Presented by Dr. Kadiyali M Srivatsa
Every day, patients walk into clinics, trusting someone will care for them. But what if I told you…
that medical errors are now the third leading cause of death in the world?
Yes—after heart disease and cancer.
And the tragedy?
Most of these deaths are preventable.
🎬 Scene 2: Medical Negligence – A Global Crisis
On Screen:
⚠️ FACT: 2.6 million deaths annually are linked to medical errors – WHO
Narration:
According to the World Health Organization,
over 2.6 million people die every year due to unsafe medical care.
In high-income countries,
1 in 10 patients is harmed while receiving hospital care.
In low- and middle-income countries…
the number is likely even higher, but underreported.
This… is a silent pandemic.
Act of Commission vs. Omission
Negligence isn’t always about what’s done. It’s often about what is not done.
Doing what shouldn’t be done. Or…
failing to do what must be done.
Both destroy lives.
Nurses Acting as Doctors
Untrained, Unsupervised, Unethical. In some systems, nurses with only 6 months of training diagnose, prescribe, and manage patients without supervision.
This is not progress. It’s cost-cutting at the cost of lives.
Since 2006, hospitals in the UK began replacing doctors with “Independent Nurse Practitioners and prescriber.”
And what happened?
Avoidable deaths doubled. Medical litigation rose to £1.5 billion. Hospitals started collapsing under the weight of compensation claims.
Real Cases – Real Suffering
On Screen:
🚨 True Stories That Shake the Soul
Narration:
A nurse tells a 23-year-old woman with yellow eyes “It’s just a flu. Take paracetamol.” Two days later, she’s in liver failure.
A young man misdiagnosed with shingles actually has septicemia—He collapses in shock. Survives—but just barely.
A toddler with pneumonia is sent home. Told to return after the weekend.
She nearly dies. These are not accidents.
These are acts of negligence. And behind every mistake… is a family left grieving.
Why did I create Dr. Maya GPT?
Dr. Maya GPT – A Global Guardian for Patient Safety. I could no longer bear to watch patients suffer due to systemic negligence,
corporate cost-cutting, and ego-driven medicine.
Dr. Maya is not a replacement for doctors.
It is a guide.
A safety net.
An AI-powered guardian that helps people identify when to seek help—
and most importantly, whom to trust.
The Ethical Compass – Diligence - A Universal Virtue Across Faiths
Whether it's the teachings of the Bible, the Quran, the Gita, or the Dhammapada -they all echo one truth:
“Act with diligence.” That means effort. Integrity.
And doing the right thing—even when no one is watching.
SOPHE navigating digital complexity for health education in 21st centiry
SOPHE navigating digital complexity for health education in 21st centiryTina Purnat This talk invites health education and health promotion professionals to reflect on their evolving role in the age of digital complexity. As digital spaces increasingly shape how people seek, share, and understand health information, educators must expand their impact beyond individuals and communities. We’ll explore how your work also needs to reach upward to senior leaders and policymakers, across to peers in communication, tech, and healthcare, and downward to support and guide newer professionals entering the field. Drawing on SOPHE competencies, this presentation emphasizes relational communication, trust-building, participatory strategies, and systems thinking as essential tools for navigating information ecosystems that are fragmented, commercialized, and emotionally charged. We’ll look at real-world examples—from reproductive health apps and social media self-diagnosis to AI-generated health content—and consider what it takes to build resilience, credibility, and connection in this new environment. Health educators are not just communicators; we are system influencers in a digital world.
Iron, Hemoglobin and bilirubin Metabolism
Iron, Hemoglobin and bilirubin MetabolismMedicoseAcademics Title: Iron and Hemoglobin Metabolism
Lecturer: Dr. Faiza
Assistant Professor of Physiology
Institution: [Your Institution's Name]
Description:
This lecture provides a thorough exploration of the essential processes involved in iron metabolism and the synthesis, function, and types of hemoglobin, with a specific focus on their roles in erythropoiesis. Dr. Faiza, Assistant Professor of Physiology, takes students through the biochemistry and physiology underlying these critical aspects of human biology. The lecture also delves into the importance of vitamin B12 and folic acid in red blood cell (RBC) maturation and the impact of iron metabolism on erythropoiesis.
Key learning objectives include:
Understanding the crucial roles of Vitamin B12 and Folic Acid in RBC maturation and their relationship with DNA synthesis.
Identifying the synthesis process and functions of Hemoglobin.
Analyzing the different types of hemoglobin and their relevance at various stages of human development.
Exploring iron metabolism, its role in the production of hemoglobin, and its essential involvement in erythropoiesis.
Discussing the metabolism of bilirubin and its clinical implications, including the development of jaundice.
The presentation also covers the important aspects of hemoglobin electrophoresis, the reversible binding of oxygen to hemoglobin, and its ability to transport carbon dioxide and nitric oxide, contributing to blood pressure regulation. Additionally, the lecture touches on metabolic disorders such as methemoglobinemia, where the iron in hemoglobin is oxidized, impairing oxygen binding.
Topics Covered:
Vitamin B12 and Folic Acid in RBC Maturation: The lecture emphasizes the role of these vitamins in DNA synthesis, with a focus on how deficiencies can lead to macrocytic anemia.
Hemoglobin Structure and Synthesis: Understanding the components of hemoglobin, including the globin chains and heme groups, and their formation process.
Types of Hemoglobin: Insight into embryonic, fetal, and adult hemoglobins, including the clinical significance of variants like HbS (sickle cell hemoglobin).
Iron Metabolism: A detailed look at how iron is absorbed, transported, and stored in the body, as well as its critical role in the production of hemoglobin.
Bilirubin Metabolism: The process of bilirubin production from RBC breakdown, including its implications for jaundice.
This lecture is designed to provide students with a deep understanding of these fundamental physiological processes, preparing them for clinical challenges and further studies in the field of hematology and physiology.
Bangkok Declaration oral health at the global radar.pdf
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molecular medicin unit 2 lecturer 1.pptx
molecular medicin unit 2 lecturer 1.pptxBolan University of Medical and Health Sciences ,Quetta Genes are formed by the order of the nitrogenous bases present in the DNA which is crucial for protein synthesis. RNA is another nucleic acid that translates genetic information into proteins from DNA. The nucleotides are linked together for the formation of two long strands. genomics, which encompasses the examination of an organism's entire set of genetic material, including DNA and RNA.
by Dr Aliya S.M
BUMHS,QTA
Pandemic Accord WHO-Ahmed-Refat-Zagazig Conference 2024
Pandemic Accord WHO-Ahmed-Refat-Zagazig Conference 2024Ahmed-Refat Refat 1.* The concept of “pathogen X” .
2.* Drawbacks and gaps in “IHR-2005”
3.* The main articles of the final version of the “proposed accord”.
4.* Point of view of hesitating and opposers bodies of the proposed accord.
5.* Benefits of the proposed accord for international health.
6.* Alternative legal instruments
Acetate mevalonate pathway (mevalonic acid pathway).pdf
Acetate mevalonate pathway (mevalonic acid pathway).pdfsamuelwadia A vivid description of the acetate mevalonate pathway, a gateway for many secondary metabolites among which are volatile oils, saponins, and cardiac glycosides.
This particular document shows the origins of monoterpenes, diterpenes, sesquiterpenoids, triterpenoids and tetraterpenoids.
Biophysics Thermodynamics 1 Chapter Notes
Biophysics Thermodynamics 1 Chapter NotesPKLI-Institute of Nursing and Allied Health Sciences Lahore , Pakistan.
Molecular Biology & Genetics cell function and structure 1.pptx
Molecular Biology & Genetics cell function and structure 1.pptxBolan University of Medical and Health Sciences ,Quetta
Best Varicose Veins Treatment in Jaipur
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